Aspirin

Aspirin

Aspirin is a white crystalline substance make of carbon, hydrogen, and oxygen. It is use in the treatment of rheumatic feverishness, headaches, neuralgia, colds, and arthritis; reduce temperature and pain. The formula for acetylsalicylic acid is CH3CO2C6H4CO2H. Aspirins scientific name is actylsalicylic acid (ASA). The main ingredient in ASA is salicylic acid. This ingredient grows in small roots, leaves, flowers and fruits on plants.

About 100 historic period ago, a German chemist, Felix Hoffmann, set out to find a drug that would ease his fathers arthritis without causing severe stomach b some otheration that came from sodium salicylate, the standard anti-arthritis treatment of the time. Hoffmann figured that the acidity of the salicylate made it hard on the stomachs lining. He began looking for a slight acidic formulation. His search led him to the synthesization of acetylsalicylic acid. The compound sh ared the remedial properties of other salicylates, but ca apply less stomach irritation. ASA reduced fever, projected moderate pain, and, at higher doses, alleviated rheumatic fever and arthritic conditions.

Though Hoffmann was confident that ASA would prove more affective than other salicylates, but his superiors incorrectly stated that ASA weakens the heart and that physicians would not take on it. Hoffmanns employer, Friedrich Bayer and Company, gave ASA its now famous name, aspirin.

        It is not yet richly known how aspirin works, but most authorities fit out that it achieves some of its effects by hindering the flow of prostaglandins. Prostaglandins are hormone-like substances that influence the elasticity of blood vessels. John Vane, Ph. D., noted that legion(predicate) forms of tissue injury were followed by the release of prostaglandins. It was proved that prostaglndins caused ignition and fever, common signs of inflammation. Vanes research showed that by blocking the flow of prostaglandins, aspirin prevented blood from aggregating and forming blood clots.

        Aspirin can be used for...

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